IDENTIFIKASI DAN POLA RESISTENSI Staphylococcus PADA PASIEN PENDERITA ULKUS DIABETIKUM DI RSUD BANYUMAS

KUSUMAH, FAISHAL PUTRA (2024) IDENTIFIKASI DAN POLA RESISTENSI Staphylococcus PADA PASIEN PENDERITA ULKUS DIABETIKUM DI RSUD BANYUMAS. Diploma thesis, UNIVERSITAS BAKTI TUNAS HUSADA TASIKMALAYA.

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Abstract

ABSTRAK GAMBARAN JENIS BAKTERI STAPHYLOCOCCUS PADA PASIEN PENDERITA ULKUS DIABETIKUM DI RSUD BANYUMAS Faishal Putra Kusumah Analis Kesehatan, Universitas Bakti Tunas Husada Abstrak Ulkus diabetikum adalah ulkus yang terinfeksi akibat kelainan pada sistem urogenital. saraf dan pembuluh darah. Jika tidak ditangani dengan benar, Infeksi dapat terjadi dapat semakin memburuk dan berujung pada amputasi. Penelitian ini bertujuan untuk menggambarkan jenis bakteri Staphylococcus dan hasil uji resistensi Staphylocccus yang ditemukan pada pasien penderita ulkus diabetikum, sampel diambil dari 18 pasien ulkus diabetikum yang dirawat di rumah sakit. Isolasi dan diidentifikasi bakteri dilakukan menggunakan alat vitex compact 2. Hasil menunjukan bahwa Staphylococcus aureus adalah spesies yang paling dominan, sebanyak 10 sampel (56%), diikuti oleh Staphylococcus haemolyticus sebanyak 5 sampel (28%), dan Staphylococcus epidermidis sebanyak 3 sampel (17%), Resistensi Staphylococcus aureus terhadap antibiotik cindamycin dan erythromycin sebanyak 2 sampel (20%); oxacillin sebanyak 3 sampel (30%); ciprofloxacin dan levofloxacin sebanyak 5 sampel (50%); moxifloxacin 6 sampel (60%); benzypenicillin sebanyak 8 sampel (80%).Resistensi Staphylococcus epidermidis terhadap antibiotik ciprofloxacin, levofloxacin, moxifloxacin, co - trimoxasole, cindamycin, erythromycin, tetracyline sebanyak 1 sampel (33%); benzypenicillin dan oxacillin sebanyak 3 sampel (100%). Resistensi Staphylococcus haemolyticus terhadap antibiotik rifampicin sebanyak 1 sampel (20%); co - trimoxasole dan tetracyline sebanyak 3 sampel (60%); gentamycin, moxifloxacin, clindamycin, sebanyak 4 sampel (80%); ciprofloxacin, levofloxacin, erythromycin, benzypenicillin, dan oxacillin sebanyak 5 sampel (100%). Penelitian ini menyoroti pentingnya deteksi dini dan identifikasi jenis bakteri pada ulkus diabetikum untuk pengelolaan infeksi yang efektif, karena adanya resistensi antibiotik yang tinggi pada beberapa Staphylococcus. Kata Kunci : Ulkus diabetikum, Stapphylococcus aureus, Staphylococcus epidermidis, Staphylococcus haemolyticus, Infeksi bakteri, Resistensi antibiotik   Abstract Diabetic ulcers are ulcers that become infected due to abnormalities in the urogenital system. nerves and blood vessels. If not treated properly, the infection can get worse and lead to amputation. This study aims to describe the types of Staphylococcus bacteria and the results of the Staphylococcus resistance test found in patients suffering from diabetic ulcers, samples were taken from 18 diabetic ulcer patients who were treated in hospital. Isolation and identification of bacteria was carried out using a vitex compact 2. The results showed that Staphylococcus aureus was the most dominant species, with 10 samples (56%), followed by Staphylococcus haemolyticus with 5 samples (28%), and Staphylococcus epidermidis with 3 samples (17 %), Resistance of Staphylococcus aureus to the antibiotics cindamycin and erythromycin in 2 samples (20%); oxacillin in 3 samples (30%); ciprofloxacin and levofloxacin in 5 samples (50%); moxifloxacin 6 samples (60%); benzypenicillin in 8 samples (80%). Resistance of Staphylococcus epidermidis to antibiotics ciprofloxacin, levofloxacin, moxifloxacin, co - trimoxasole, cindamycin, erythromycin, tetracyline in 1 sample (33%); benzypenicillin and oxacillin in 3 samples (100%). Staphylococcus haemolyticus resistance to the antibiotic rifampicin was 1 sample (20%); co - trimoxasole and tetracycline in 3 samples (60%); gentamicin, moxifloxacin, clindamycin, 4 samples (80%); ciprofloxacin, levofloxacin, erythromycin, benzypenicillin, and oxacillin in 5 samples (100%). This study highlights the importance of early detection and identification of bacterial types in diabetic ulcers for effective management of infection, due to the high antibiotic resistance of some Staphylococcus. Keywords: Diabetic ulcer, Stapphylococcus aureus, Staphylococcus epidermidis, Staphylococcus haemolyticus, Bacterial infection, Antibiotic resistance

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