AKTIVITAS PENURUNAN INDEKS OBESITAS EKSTRAK ETANOL RUMPUT LAUT (Eucheuma spinosum.) PADA MENCIT (Mus Muscullus) SWISS WEBSTER

Triana, Irma (2024) AKTIVITAS PENURUNAN INDEKS OBESITAS EKSTRAK ETANOL RUMPUT LAUT (Eucheuma spinosum.) PADA MENCIT (Mus Muscullus) SWISS WEBSTER. Sarjana thesis, UNIVERSITAS BAKTI TUNAS HUSADA TASIKMALAYA.

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Abstract

Obesity is one of the health problems on childrens and adults. Eucheuma Spinosum is a plant that has the potential to reduce obesity. To determine the effect of seaweed ethanol extract (Eucheuma Spinosum) on decreasing of obesity index in white mice fed a high-fat diet. Laboratory experimental research used test animals, namely white mice which were divided into 6 groups (Negative and positive control, dose 1 (0.84 mg/kg BB), Dose 2 (1.68,) and dose 3 (3.36 mg/kg BB of mice) Mice inducted with high-fat feed for 14 days. Furthermore, all mice were given seaweed ethanol extract for 14 days starting on the 15th day, then checked for obesity index. The data was analysed with Kruskall wallis and Man Whitney (α = 0.05). The study showed that Echeuma Spinosum seaweed ethanol extract contains Alcaloids, Flavonoids, Tannin, Poliphenols. Saponins. There were a significant difference between the treatment groups with a value (p=0.034) on reducing obesity index. Echeuma Spinosum seaweed ethanol extract effective on decreasing the obesity index which 1,68 mg/kg BB of mice was the best dose (26.75%). Keywords: Obesity; Seaweed extract, High fat feed

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