STUDI FARMAKOVIGILANS OBAT GOLONGAN ANTIPSIKOTIK PADA PASIEN SKIZOFRENIA DI RSUD SMC KABUPATEN TASIKMALAYA

Salsabila, Siti Salma (2022) STUDI FARMAKOVIGILANS OBAT GOLONGAN ANTIPSIKOTIK PADA PASIEN SKIZOFRENIA DI RSUD SMC KABUPATEN TASIKMALAYA. Sarjana thesis, Universitas BTH Tasikmalaya.

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Abstract

ABSTRAK Skizofrenia adalah salah satu jenis penyakit gangguan jiwa disertai beberapa gejala diantaranya halusinasi, delusi, gangguan proses berpikir dan prilaku aneh. Penelitian ini bertujuan mengetahui jenis obat golongan antipsikotik yang sering digunakan, evaluasi obat yang mencakup penilaian, pemahaman juga gejala dan efek samping setelah mengkonsumsi obat golongan antipsiotik pada pasien skizofrenia di RSUD SMC Kabupaten Tasikmalaya. Jenis penelitian ysng digunakan ialah observasional dengan desain penelitian cross sectional dan pengambilan data dilakukan secara prospektif. Hasil penelitian menunjukan bahwa penggunaan obat golongan antipsikotik yang paling banyak ialah kombinasi dengan obat jenis lain sebanyak 60 orang dan penggunaan obat golongan antipsikotik kedua (atipikal) tunggal sebanyak 20 orang clozapine 85% dan risperidone 15%. Gejala yang palng banyak pada pasien skizofrenia gejala positif 71% dan negatif 29%, efek samping yang sering muncul yakni sedasi 32%. Evaluasi obat berdasarkan ketepatan indikasi dan dosis 100%. Hasil analisis menunjukan semua hasil data demografi tidak terdapat hubungan dengan efek samping obat yang muncul, efek samping obat mayoritas disebabkan oleh obat itu sendiri. Kata kunci : skizofrenia, farmakovigilans, antipsikotik ABSTRACT Schizophrenia is a type of mental illness accompanied by several symptoms including hallucinations, delusions, delusions, disturbances in thought processes and strange behavior. This study aims to determine the types of antipsychotic group drugs that are often used, drug evaluation which includes assessment, understanding also symptoms and side effects after taking antipsychotic group drugs in schizophrenic patients at SMC Hospital Tasikmalaya Regency. The results showed that the most use of antipsychotic group drugs was a combination with other types of drugs as many as 60 people and the use of a single second (atypical) antipsychotic group drug as many as 20 people clozapine 85% and risperidone 15%. The symptoms that palng a lot in schizophrenic patients are 71% positive symptoms and 29% negative, the side effects that often appear are 32% sedation. Evaluation of the drug based on the correctness of indications and 100% dosage. The results of the analysis showed that all demographic data results had no relationship with the side effects of the drugs that appeared, the majority of drug side effects were caused by the drugs themselves. Keywords : schizophrenia, pharmacovigilance, antipsychotic OLEH : SITI SALMA SALSABILA 31118189

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