Febriany, Queeny Amalia (2024) PEMERIKSAAN KARAKTERISTIK MUTU SIMPLISIA DAN UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL RANTING JENGKOL (Archidendron pauciflorum) TERHADAP BAKTERI STREPTOCOCCUS MUTANS PENYEBAB KARIES GIGI. Sarjana thesis, UNIVERSITAS BAKTI TUNAS HUSADA.
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Abstract
ABSTRAK Pemeriksaan Karakteristik Mutu Simplisia dan Uji Aktivitas Ekstrak Etanol Ranting Jengkol (Achidendron pauciflorum) Terhadap Bakteri Streptococcus mutas Penyebab Karies Gigi Queeny Amalia Febriany Prodi S1 Farmasi, Universitas Bakti Tunas Husada Tasikmalaya Abstrak Karies gigi merupakan permasalahan kesehatan gigi yang banyak ditemukan di kalangan masyarakat..Menurut data empiris, ranting jengkol bisa mengatasi masalah pada gigi yang disebabkan oleh bakteri.Tujuan penelitian untuk mengetahui karakteristik mutu simplisia dan aktivitas antibakteri ekstrak etanol ranting jengkol (Archidendron pauciflorum) terhadap bakteri Streptococcus mutans penyebab karies gigi. Penelitian ini dimulai dengan pemeriksaan mutu simplisia, ekstraksi dengan metode maserasi menggunakan pelarut etanol 96%. Hasil uji aktivitas konsentrasi 50% menghasilkan 17,96 mm, konsentrasi 40% menghasilkan 16,5 mm, konsentrasi 30% menghasilkan 15,7 mm, konsentrasi 20% menghasilkan 15 mm, konsentrasi 10% 12 mm, kontrol positif menghasilkan 18,4 mm, kontrol negatif menghasilkan 7 mm. Kesimpulannya konsentrasi 50% terbukti efektif dalam menghambat aktivitas antibakteri Streptococcus mutans, karena sebanding dengan kontrol positif yaitu clindamycin. Kata Kunci : karies gigi, tanaman jengkol, streptococcus mutans, aktivitas antibakteri. Abstract Dental caries is a dental health problem that is often found among the public. According to empirical data, jengkol twigs can overcome dental problems caused by bacteria. The aim of the research is to determine the quality characteristics of simplicia and the antibacterial activity of the ethanol extract of jengkol twigs (Archidendron pauciflorum) against bacteria. Streptococcus mutans causes dental caries. This research began with a quality inspection of simplicia, extraction using the maceration method using 96% ethanol solvent. Activity test results of 50% concentration produced 17.96 mm, 40% concentration produced 16.5 mm, 30% concentration produced 15.7 mm, 20% concentration produced 15 mm, 10% concentration 12 mm, positive control produced 18.4 mm , the negative control yielded 7 mm. In conclusion, a concentration of 50% proved effective in inhibiting the antibacterial activity of Streptococcus mutans, because it was comparable to the positive control, namely clindamycin.. Keywords: dental caries, jengkol plant, streptococcus mutans, antibacterial activity.
Item Type: | Thesis (Sarjana) |
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Subjects: | S1-Skripsi Farmasi |
Divisions: | Prodi Farmasi |
Depositing User: | S.Farm. Queeny Amalia Febriany |
Date Deposited: | 11 Sep 2024 02:17 |
Last Modified: | 11 Sep 2024 02:18 |
URI: | https://repository.universitas-bth.ac.id/id/eprint/3889 |
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